| ★ |  The Queen Ended My FIRST Slay the Spire 2 Run! | | 30 | — | |
| 3 |  Silent Infinite Is Even More Powerful Now... (Slay The Spire 2) #slaythespire #slaythespire2 | Michael Tsoob @michaeltsoob | 1.0M | Rumanía | 90 |
| 6 |  How To Exploit Vakuu's "Blessing" #slaythespire #gaming #slaythespire2 | Michael Tsoob @michaeltsoob | 954.6K | Rumanía | 90 |
| 14 |  Whoops! I've Been IGNORING Some Good Upgrades! #slaythespire | Jeremy Bentham @jeremy_bentham | 749.9K | — | 89 |
| 11 |  They made a sequel to the game that ruined my life | | 549.2K | Japón | 89 |
| 9 |  These Basic Enemies Are RIDICULOUS! #slaythespire #ranking | Jeremy Bentham @jeremy_bentham | 525.2K | — | 89 |
| 1 |  65 hours of playtime - I FINALLY beat Slay the Spire 2 😁🎮 #steamdeck #slaythespire #gaming #gym | Carter Powers @iamcarterpowers | 163.7K | — | 91 |
| 2 |  My first ever infinite build in Slay The Spire 2 😁😁😁😁 #slaythespire #steamdeck #gaming #gym | Carter Powers @iamcarterpowers | 113.3K | — | 91 |
| 4 |  I accidentally killed the merchant in Slay the Spire 2 😳 #steamdeck #gaming #slaythespire #gym | Carter Powers @iamcarterpowers | 112.7K | — | 90 |
| 15 |  Check Out - Slay The Spire 2 | Mortismal Gaming @mortismalgaming | 92.8K | Estados Unidos | 89 |
| 13 |  Easy Infinite Build On The Silent (Slay The Spire) | Michael Tsoob @michaeltsoob | 81.2K | Rumanía | 89 |
| 20 |  We Killed EVERY ENEMY in One Run | | 35.2K | Estados Unidos | 89 |
| 18 |  I Installed a Slay the Spire 2 Randomizer Mod | | 32.3K | Estados Unidos | 89 |
| 19 |  Fighting a boss in ARC Raiders | LiterallyRay @literallyray | 8.1K | Estados Unidos | 89 |
| 12 |  You Need to Play Slay the Spire 2 Right Now #deckbuilder #shorts | TheElusiveSquirrel @theelusivesquirrel | 5.6K | Estados Unidos | 89 |
| 8 |  I Challenged the Silver Queen…This Was Brutal | Absolum | | 114 | — | 89 |
| 5 |  I Refused To Die… - Vampire Crawlers | | 97 | — | 90 |
| 7 |  The Shiv Deck Got Out Of Control! | | 59 | — | 90 |
| 17 |  I Found My New Favorite Card! | | 28 | — | 89 |
| 10 |  Game Over: Slay “The Spire” II | enred andaluciatv @enredandaluciatv423 | 24 | — | 89 |